Molecular mechanisms of <i>cis</i>‐urocanic acid and permethrin‐induced alterations in cutaneous immunity

Abstract

These results suggest the following: (1)Mouse strains show variable susceptibility to permethrin- and cUCA-induced immunomodulation. (2)TNFalpha may be involved in the immunomodulatory effects of cUCA and permethrin. (3)IFNgamma may be required for the more than additive depression of CH caused by cUCA+permethrin.