Organosilicon(IV) and organotin(IV) complexes as biocides and nematicides: synthetic, spectroscopic and biological studies of N^∩N donor sulfonamide imine and its chelates

Abstract

Abstract A brief account is given of the synthesis and stereochemistry and the antibacterial, antifungal, nematicidal and insecticidal behaviour of organosilicon(IV) and organotin(IV) complexes of a biologically potent ligand, 2‐acetylfuransulfaguanidine. The unimolar and bimolar substitution products have been characterized by elemental analyses, conductance measurements, molecular weight determinations, and spectral studies, viz. IR, 1 H NMR, 13 C NMR, UV, 29 Si NMR and 119 Sn NMR spectra. The data support the binding of the nitrogen atom to the metal atom in R 3 M(N ∩ N), [R 2 M(N ∩ N) 2 and R 2 M(N ∩ N)Cl [(R = Me/Ph and M = Si(IV) and Sn(IV)] types of complex. Based on these studies, with coordination number five and six a trigonal bipyramidal and an octahedral geometry have been proposed for the resulting derivatives. The free ligand (N ∩ NH) and its respective metal complexes were tested in vitro against a number of microorganisms to assess their antimicrobial properties. The results are indeed positive. In addition to these studies, the complexes also show good nematicidal and insecticidal properties. The results of these findings have been discussed in detail. Copyright © 2004 John Wiley & Sons, Ltd.