Distribution of Myocilin and Extracellular Matrix Components in the Corneoscleral Meshwork of Human Eyes

Abstract

This study illustrated the composition of ECM materials in the trabecular lamellae of CS meshwork. Myocilin was specifically localized to long-spacing collagens and the surrounding sheath of elastic-like fibers interacting with microfibril-associated elements where changes have been documented to occur in glaucomatous and aging eyes.