Archives of Pediatrics and Adolescent Medicine · 1949 · 40 citations · 21 references
EducationHuman DevelopmentPediatricsChild DevelopmentDevelopmental AnatomyDevelopmental PediatricsChild GrowthGrowth AssessmentOral DevelopmentPubertySexual DevelopmentSexual MaturationEarly PubertySexual Development AssessmentSocioeconomic Background
A GENERAL discussion of the problems involved in precocious sexual development of children was presented by one of us (H. P. G. S.) in 1946.<sup>1</sup>This publication and another one to follow are intended to amplify that general discussion with a presentation of 6 specific examples. The first of these publications deals with diagnostic and pathogenetic studies, while the second will be devoted to the aspects of growth and maturation in the same patients.<sup>2</sup>From the beginning, it seems to be of paramount importance to recognize the borderline between pathologic "precocity" of sexual development and what may be termed physiologic "early" sexual development. A few observations on the latter group of children may be briefly recorded with a view to avoiding diagnostic pitfalls and the consequences of calling children abnormal who are exuberantly healthy. <h3>I. "EARLY" SEXUAL DEVELOPMENT</h3> In normal boys "early" sexual development is rarer than in
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BILATERAL ADRENALECTOMY IN PROSTATIC CANCER
Charles Huggins, William W. Scott · Annals of Surgery · 1945 · 348 citations
Normal Excretion of Sex Hormones in Childhood.<sup>1</sup>
Ira T. Nathanson, LOIS E. TOWNE, Joseph C. Aub · Endocrinology · 1941 · 102 citations
Medicine, Endocrinology, Physiology +17
PRECOCIOUS PUBERTY AND TUMORS OF THE HYPOTHALAMUS
LAURENCE M. WEINBERGER · Archives of internal medicine · 1941 · 95 citations
Medicine, Endocrinology, Pediatrics +17