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Thyrotropin-Secreting Adenoma in an Adolescent Girl without Increased Serum Thyrotropin-alpha
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1994
Year
Inappropriate Tsh SecretionTsh SecretionThyroid DiseaseParathyroid DiseaseGynecologyPathologyThyroid DisordersThyroid HormonesPituitary DiseaseParathyroid GlandEndocrinologyMedicineThyrotropin-secreting AdenomaEndocrine DiseaseReproductive Endocrinology
A 13-year-old girl with poor weight gain and pubertal delay was referred for hyperthyroidism. Slightly elevated levels of circulating thyroid hormones failed to suppress circulating thyrotropin (TSH) levels. Despite appropriate thyrotropin-releasing hormone stimulation of TSH secretion, a thyrotropin-secreting pituitary adenoma was identified as the cause of inappropriate TSH secretion.