Highly Enantioselective Intramolecular Copper Catalyzed C−H Insertion Reactions of α-Diazosulfones

Abstract

Excellent enantiocontrol (up to 98% ee) is achieved in copper catalyzed C-H insertions of alpha-diazosulfones to form thiopyrans, with up to 60% ee in C-H insertions leading to sulfolanes.