Augmentation of Behavior Therapy With <scp>d</scp> -Cycloserine for Obsessive-Compulsive Disorder

Abstract

These data provide support for the use of D-cycloserine as an augmentation of behavior therapy for OCD and extend findings in animals and other human disorders suggesting that behavior therapy acts by way of long-term potentiation of glutamatergic pathways and that the effects of behavior therapy are potentiated by an NMDA agonist.