Concepedia

Publication | Open Access

Protease profiling of liver fibrosis reveals the ADAM metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of transforming growth factor beta

DOIFull Paper Access

92

Citations

30

References

2010

Year

Katia Bourd‐Boittin, Dominique Bonnier, Anthony Leyme, Bernard Mari, Pierre Tufféry, Michel Samson, Frédéric Ezan, Georges Baffet, Nathalie Théret
Hepatology

Abstract

Our results indicate that up-regulation of ADAMTS1 in HSCs constitutes a new mechanism for control of TGF-β activation in chronic liver disease.

References

YearCitations

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