Papuloerythroderma of Ofuji responding to treatment with cyclosporin

Abstract

We describe a patient with papuloerythroderma of Ofuji (PE) of unknown cause, in whom no underlying malignancy was found. Topical steroids and systemic antihistamines did not resolve the rash. Systemic steroids induced a remission of the PE, which was not maintained on reduction of the dose. Therefore, cyclosporin was added which did lead to rapid clearing of the skin. Remission was maintained after discontinuation of treatment.