Concepedia

Intracellular IL-1Ra type 1 inhibits IL-1-induced IL-6 and IL-8 production in Caco-2 intestinal epithelial cells through inhibition of p38 mitogen-activated protein kinase and NF-κB pathways

Chrystelle Garat

Cytokine · 2003 · 94 citations · 24 references

DOI

Concepts

References

24

Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine

Joël Raingeaud, Shashi Kumar Gupta, Jeffrey S. Rogers et al. · Journal of Biological Chemistry · 1995 · 2.2K citations · Full text

, , +17

Independent Human MAP-Kinase Signal Transduction Pathways Defined by MEK and MKK Isoforms

Benoît Dérijard, Joël Raingeaud, Tamera Barrett et al. · Science · 1995 · 1.6K citations

, , +13

IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK

John Woronicz, Xiong Gao, Zhaodan Cao et al. · Science · 1997 · 1.2K citations

, , +16

cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily

John E. Sims, Caril J. March, David Cosman et al. · Science · 1988 · 892 citations

, , +12

CREB-binding protein/p300 are transcriptional coactivators of p65

Mary E. Gerritsen, Amy J. Williams, Andrew S. Neish et al. · Proceedings of the National Academy of Sciences · 1997 · 825 citations

, , +13