Archives of Ophthalmology · 1945 · 23 citations · 0 references
MedicineAnatomyOphthalmologyEyelid DisordersHuman GeneticsOculoplasticsCongenital Craniofacial AnomaliesCongenital Eye AnomaliesCongenital Head AnomaliesCraniofacial AnomaliesEyelid MalformationsCongenital Facial AsymmetryCongenital Midface AnomaliesEyelid Developmental AnomaliesEyelid Margin NotchingLid ColobomaLower Eyelid AnatomyLower Eyelid Malformations
In 1888 Berry<sup>1</sup>described symmetric notches in the outer portion of the lower lids in a mother whose daughter had a similar defect in one lower eyelid. Although Berry did not examine the mother's brother, the latter reputedly had a similar defect in one eye. The affected child's brother had no ocular defect but a harelip, and her older sister showed no clinical defects. In 1900 Treacher Collins<sup>2</sup>recorded 2 cases of symmetric congenital notching in the outer part of each lower lid associated with clinical evidence of defective development of the malar bones. The family history was negative for the condition in 1 case and was not mentioned in the other. In 1927 Isakowitz<sup>3</sup>described a similar case of symmetric notching of the outer portion of each lower lid. He stated the opinion that these defects were probably colobomas. Although he did not examine the father