Hydrogels based on gelatin poly(hydroxyethyl methacrylate) and poly(butyl acrylate) graft copolymer impregnated with fibrin

Abstract

Gelatin was graft copolymerized with poly(hydroxyethyl methacrylate and butyl acrylate) and subsequently crosslinked with glutaraldehyde. Fibrin of bovine origin was incorporated onto this graft copolymer and characterized for the percentage of grafting. The infrared spectroscopy, mechanical strength, and water absorption capacity of the composite were also studied. This biomaterial can be used as a hemostat in many phases of surgery and as a wound dressing material. © 1997 John Wiley & Sons, Inc. J Appl Polym Sci 65:555–560, 1997