Concepedia

Effect of hydrophobic interaction cooperating with double Lewis acid activation in a zinc(ii) phosphodiesterase mimic

Meng Zhao, Li Zhang, Huo‐Yan Chen, Hanlu Wang, Liang‐Nian Ji, Zong‐Wan Mao

Chemical Communications · 2010 · 27 citations · 25 references

DOI

Concepts

Abstract

The novel dinuclear Zn(ii) complex (1) containing a beta-CD dimer could accelerate BNPP (a DNA substitute) hydrolysis more efficiently than catalyze HPNP (a RNA substitute) transesterification with different mechanisms involved; the beta-CDs played remarkably different roles.

References

25

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Norbert Sträter, William N. Lipscomb, Thomas Klabunde et al. · Angewandte Chemie International Edition in English · 1996 · 612 citations

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Structure and Nuclease Activity of Simple Dinuclear Metal Complexes:  Quantitative Dissection of the Role of Metal Ions

Nicholas H. Williams, Bryan K. Takasaki, Mark Wall et al. · Accounts of Chemical Research · 1999 · 549 citations

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"Artificial enzyme" combining a metal catalytic group and a hydrophobic binding cavity

Ronald Breslow, Larry E. Overman · Journal of the American Chemical Society · 1970 · 347 citations

, , +15

Cooperative Binding and Multiple Recognition by Bridged Bis(<i>β</i>-cyclodextrin)s with Functional Linkers

Yu Liu, Yong Chen · Accounts of Chemical Research · 2006 · 305 citations

, , +15

Physical and Kinetic Analysis of the Cooperative Role of Metal Ions in Catalysis of Phosphodiester Cleavage by a Dinuclear Zn(II) Complex

Olga Iranzo, Andrey Kovalevsky, Janet R. Morrow et al. · Journal of the American Chemical Society · 2003 · 232 citations

, , +17