Concepedia

Targeting glucosylceramide synthase downregulates expression of the multidrug resistance gene MDR1 and sensitizes breast carcinoma cells to anticancer drugs

Yanlin Sun, Tingguo Zhang, Peng Gao, Bin Meng, Yongsheng Gao, Xiao Wang, Jianping Zhang, Hao Wang, Xiaojuan Wu, Wenxin Zheng,

Breast Cancer Research and Treatment · 2009 · 30 citations · 27 references

DOI

Concepts

References

27

NF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells

Mohamed Bentires‐Alj, Véronique Barbu, Marianne Fillet et al. · Oncogene · 2003 · 430 citations · Full text

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Accumulation of Glucosylceramides in Multidrug-resistant Cancer Cells

Yaakov Lavie, Hui-Ting Cao, Stuart L. Bursten et al. · Journal of Biological Chemistry · 1996 · 342 citations · Full text

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Expression of Glucosylceramide Synthase, Converting Ceramide to Glucosylceramide, Confers Adriamycin Resistance in Human Breast Cancer Cells

Yu Liu, Tie-Yan Han, Armando E. Giuliano et al. · Journal of Biological Chemistry · 1999 · 269 citations · Full text

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A Single siRNA Suppresses Fatal Encephalitis Induced by Two Different Flaviviruses

Priti Kumar, Sang Kyung Lee, Premlata Shankar et al. · PLoS Medicine · 2006 · 180 citations · Full text

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The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells

Michelle L. Holland, Jill Panetta, Janelle M. Hoskins et al. · Biochemical Pharmacology · 2006 · 156 citations

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