Peroxisome proliferator activated receptor gamma activity is low in mature primary human visceral adipocytes

Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension

Inês Barroso, Mark Gurnell, Vivion Crowley et al. · Nature · 1999 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +12

The Influence of Body Fat Distribution on the Incidence of Diabetes Mellitus: 13.5 Years of Follow-up of the Participants in the Study of Men Born in 1913

L.‐O. Ohlson, B. Larsson, Kurt Svärdsudd et al. · Diabetes · 1985 · 984 citations

Medicine, Cardiology, Endocrinology +15

Absence of an Effect of Liposuction on Insulin Action and Risk Factors for Coronary Heart Disease

Samuel Klein, Luigi Fontana, V. Leroy Young et al. · New England Journal of Medicine · 2004 · 904 citations · Full text

Medicine, Cardiology, Endocrinology +17

Angiotensin Type 1 Receptor Blockers Induce Peroxisome Proliferator–Activated Receptor-γ Activity

Michael Schupp, Jürgen Janke, R. Clasen et al. · Circulation · 2004 · 710 citations

Medicine, Endocrinology, Pharmacology +17

Association Between Regional Adipose Tissue Distribution and Both Type 2 Diabetes and Impaired Glucose Tolerance in Elderly Men and Women

Bret H. Goodpaster, Shanthi Krishnaswami, Helaine E. Resnick et al. · Diabetes Care · 2003 · 617 citations · Full text

Medicine, Endocrinology, Geriatric Medicine +16