Studying the effect of particle size and coating type on the blood kinetics of superparamagnetic iron oxide nanoparticles

Abstract

In this report we systematically demonstrated that both particle size and coating material influence blood kinetics and magnetic properties of SPIO independently. These data provide key information for the selection of a contrast agent for a defined application and are additionally valuable for other nano areas, such as hyperthermia, drug delivery, and nanotoxicology.