Concepedia

Highly Enantioselective Quinoline Synthesis via Ene-type Cyclization of 1,7-Enynes Catalyzed by a Cationic BINAP−Palladium(II) Complex

Manabu Hatano, Kōichi Mikami

Journal of the American Chemical Society · 2003 · 158 citations · 9 references

DOI

Concepts

Abstract

The first highly enantioselective synthesis of a six-membered ring quinoline catalyzed by a cationic BINAP-palladium(II) complex is shown to afford the quinoline products having a quaternary carbon center or a spiro-ring in quantitative yield and >99% ee.

References

9

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Catalytic Enantioselective Reissert-Type Reaction:  Development and Application to the Synthesis of a Potent NMDA Receptor Antagonist (−)-L-689,560 Using a Solid-Supported Catalyst

Masahiro Takamura, Ken Funabashi, Motomu Kanai et al. · Journal of the American Chemical Society · 2001 · 182 citations

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Asymmetric Heck Reaction−Carbanion Capture Process. Catalytic Asymmetric Total Synthesis of (−)-Δ<sup>9(12)</sup>-Capnellene

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Palladium-catalyzed synthesis of 2-quinolone derivatives from 2-iodoanilines

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Highly Enantioselective Palladium-Catalyzed Ene-Type Cyclization of a 1,6-Enyne

Manabu Hatano, Masahiro Terada, Köichi Mikami · Angewandte Chemie International Edition · 2001 · 133 citations

, , +9