Cytogenetic and Genome Research · 2003 · 104 citations · 30 references
Life SciencesDevelopmental BiologyGeneticsComparative GenomicsFish BiologyGenomicsFish Comparative GenomicsFish Developmental BiologyFish GenomicsFreshwater Fish GeneticsComparative Fish GenomicsComparative Genome AnalysisEarly Vertebrate DevelopmentSex ChangeSex Determination GenesSex Determination In FishZebrafish Developmental Models
Complex developmental mechanisms of vertebrates are unraveled using comparative genomic approaches. Several teleosts, such as zebrafish, medaka and pufferfish, are used as genetic model systems because they are amenable to studies of gene function. The rice field eel, a freshwater fish, is emerging as a specific model system for studies of vertebrate sexual development because of its small genome size and naturally occurring sex reversal. Data presented here support the use of the rice field eel as another important fish model for comparative genome studies, especially in vertebrate sexual development. This model system is complementary rather than redundant.
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Male development of chromosomally female mice transgenic for Sry
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DMY is a Y-specific DM-domain gene required for male development in the medaka fish
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