P-Adic Numbers Ultrametric Analysis and Applications · 2009 · 103 citations · 11 references
Life SciencesGeneticsMolecular BiologyMolecular EvolutionGenetic CodeNucleic Acid ModelingNucleic Acid StructureDna Sequence AnalysisDna Sequence CompositionGenetic Code EvolutionP-adic FieldsP-adic IntegrationP-adic L-functionsP-adic Uniformization
Using basic properties of p-adic numbers, we consider a simple new approach to describe main aspects of DNA sequence and the genetic code. In our investigation central role plays an ultrametric p-adic information space whose basic elements are nucleotides, codons and genes. We show that a 5-adicmodel is appropriate for DNA sequence. This 5-adicmodel, combined with 2-adic distance, is also suitable for the genetic code and for amore advanced employment in genomics. We find that genetic code degeneracy is related to the p-adic distance between codons.
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R. Rammal, G. Toulouse, M. A. Virasoro · Reviews of Modern Physics · 1986 · 759 citations
Lee Brekke · Physics Reports · 1993 · 276 citations