Upregulation of Retinal Neuronal MCP-1 in the Rodent Model of Diabetic Retinopathy and Its Function In Vitro

Abstract

Upregulation of MCP-1 began during the early stage of DR and increased with the development of the disease. Retinal neurons are the main source of MCP-1, and they play an important role in retinal microglial activation, which may be an important link in the pathogenesis of DM.