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Reaction of 5-enol-pyruvoylshikimate-3-phosphate synthase with diethyl pyrocarbonate: Evidence for an essential histidine residue

BiosynthesisBioorganic ChemistryBiochemistryNatural SciencesBiocatalysisEnzyme Catalysis5-Enol-pyruvoylshikimate-3-phosphate SynthaseMolecular BiologyNatural Product BiosynthesisEnzymatic ModificationStructure-function Enzyme KineticsDiethyl PyrocarbonateEssential Histidine Residue