European Addiction Research · 2001 · 10 citations · 1 references
MedicinePharmacologyPharmacotherapyPsychopharmacologySubstance Use DisordersSuicide PreventionAddictionDrug DependenceDrug Overdose PreventionOverdose PreventionRelapse PreventionSubstance Abuse PreventionAddiction Medicine ReviewDrug Use Relapse PreventionHeroin Overdose PreventionNaloxone EfficacyNaltrexone TreatmentOpioid Overdose ManagementRelapse Prevention After OverdoseSubstance Use Disorder Pharmacotherapy
This case describes a heroin addict who was participating in a placebo-controlled randomized trial of naltrexone as an aid to relapse prevention. The patient tried to commit suicide by taking a heroin overdose after learning that he was HIV-positive. He was on naltrexone at the time and, as a result, survived what would probably have been a fatal overdose. This case demonstrates that naltrexone can have immediate as well as long-term positive effects in persons who are attempting to recover from heroin addiction.
1
Naltrexone pharmacotherapy for opioid dependent federal probationers
James Cornish, David S. Metzger, George Woody et al. · Journal of Substance Abuse Treatment · 1997 · 218 citations · Full text