PharmacyPharmacologyPharmacotherapyPulmonary Drug DeliveryPulmonologyRespiratory PharmacotherapyAerosol TherapyBronchodilator TherapyInhalation Dosage FormsInhalation TherapyMetered-dose InhalersRespiratory MedicineAsthma Medication Inhalation DevicesBronchodilator DosingMetered-dose Inhaler UsePressurized Inhaler TechniquePressurized Metered Dose InhalersTherapeutic Aerosol Safety
Patient error in use of bronchodilator metered aerosols Aerosolised bronchodilator drugs in pressurised canisters delivering metered doses are widely used, easy to carry, and apparently easy to operate.The instructions with each canister are reasonably clear, stating that each puff must be deeply inhaled and the breath held afterwards.Since the drug intake depends mostly on the patient's ability to follow the instructions, we thought it was important to find out whether asthmatics used their aerosols correctly.
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Arthur B. DuBois, Stella Y. Botelho, Julius H. Comroe · Journal of Clinical Investigation · 1956 · 1.3K citations · Full text
Medicine, Anatomy, Physiology +15