Publication | Closed Access
A Single Daily Dose of a New Form of Amitriptyline in Depressive Illness
15
Citations
1
References
1972
Year
Psychotropic MedicationPsychopharmacologyPharmacotherapySocial SciencesNon-pharmacological InterventionMedicinal ChemistryPharmacological StudyCommon Clinical ExperienceMood SymptomPharmacologic InterventionPsychoactive DrugNew FormPsychiatryDepressionNeuropharmacologyPharmacologySide EffectSingle Daily DoseSustained Release FormAddictionDepressive IllnessDrug DiscoveryBiological PsychiatryMedicinePsychopathologyPharmacoepidemiology
In order to try to overcome the common clinical experience of patients who do not take the drugs prescribed for them (Wilcox et al. , 1965) a sustained release form of amitriptyline (Lentizol) has recently been made available. This trial was undertaken to test the efficacy of this formulation given once daily at night compared to standard amitriptyline given thrice daily.
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