Concepedia

Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic β-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1)

Vaibhav Sidarala, Rajakrishnan Veluthakal, Khadija Syeda, Cornelis P. Vlaar, Philip Newsholme, Anjaneyulu Kowluru

Biochemical Pharmacology · 2015 · 41 citations · 32 references

DOIFull text

Open access

Concepts

References

32

Novel Competitive Inhibitor of NAD(P)H Oxidase Assembly Attenuates Vascular O<sub>2</sub><sup>−</sup>and Systolic Blood Pressure in Mice

Federico E. Rey, Arash Kiarash, Mark T. Quinn et al. · Circulation Research · 2001 · 606 citations

, , +17

Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

Corinne Leloup, Cécile Tourrel‐Cuzin, Chr̀istophe Magnan et al. · Diabetes · 2008 · 358 citations · Full text

, , +17

Characterization of EHop-016, Novel Small Molecule Inhibitor of Rac GTPase

Brenda L. Montalvo-Ortiz, Linette Castillo‐Pichardo, Eliud Hernandez O'Farril et al. · Journal of Biological Chemistry · 2012 · 253 citations · Full text

, , +15

Regulation of PKD by the MAPK p38δ in Insulin Secretion and Glucose Homeostasis

Grzegorz Sumara, Ivan Formentini, Stephan C. Collins et al. · Cell · 2009 · 243 citations · Full text

, , +16

Rac1 Is Required for Cardiomyocyte Apoptosis During Hyperglycemia

Enhui Shen, Yan-Wen Li, Ying Li et al. · Diabetes · 2009 · 185 citations · Full text

, , +15