Bis-Quinolinium Cyclophanes: 8,14-Diaza-1,7(1,4)-diquinolinacyclotetradecaphane (UCL 1848), a Highly Potent and Selective, Nonpeptidic Blocker of the Apamin-Sensitive Ca²⁺-Activated K⁺ Channel

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXTBis-Quinolinium Cyclophanes: 8,14-Diaza-1,7(1,4)-diquinolinacyclotetradecaphane (UCL 1848), a Highly Potent and Selective, Nonpeptidic Blocker of the Apamin-Sensitive Ca2+-Activated K+ ChannelJian-Qing Chen, Dimitrios Galanakis, C. Robin Ganellin, Philip M. Dunn, and Donald H. JenkinsonView Author Information Departments of Chemistry and Pharmacology, University College London, Gower Street, London WC1E 6BT, U.K., and Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotelian University of Thessaloniki, Thessaloniki 540 06, Greece Cite this: J. Med. Chem. 2000, 43, 19, 3478–3481Publication Date (Web):August 31, 2000Publication History Received10 January 2000Published online31 August 2000Published inissue 1 September 2000https://pubs.acs.org/doi/10.1021/jm000904vhttps://doi.org/10.1021/jm000904vrapid-communicationACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views271Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Aromatic compounds,Hydrocarbons,Molecular structure,Particulate matter,Rodent models Get e-Alerts