JAMA · 1978 · 207 citations · 7 references
Life SciencesInfectious DiseasesMicrobiologyBacteriologyDiagnostic MicrobiologyMedical MicrobiologyBacterial InfectionsBone InfectionsChronic Bone InfectionDiagnostic BacteriologyOsteomyelitisCausative PathogensMicrobiology Of OsteomyelitisSinus Culture Diagnostics
Sinus-tract cultures were compared with cultures of operative specimens from 40 patients with chronic osteomyelitis. Thirty-five patients (87.5%) had a single pathogen isolated from their operative specimens. Only 44% of the sinus-tract cultures contained the operative pathogen. Isolation of Staphyloccus aureus from sinus tracts correlated with the presence of S aureus in the operative specimen. However, less than half of the sinus-tract cultures obtained from patients with S aureus osteomyelitis contained this organism. Isolation of bacteria other than S aureus from sinus tracts had a low likelihood of predicting the pathogen isolated from bone. A presumptive diagnosis of S aureus osteomyelitis is justified if S aureus is isolated from an associated sinus tract. A bacteriologic diagnosis of chronic osteomyelitis based on isolation of common pathogens other than S aureus from sinus tracts must be verified by an appropriate operative culture.
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Chronic osteomyelitis. I. Factors affecting the results of treatment in 186 patients
W. F. West · JAMA · 1970 · 37 citations
Nonsporulating anaerobic bacteria in osteomyelitis.
Irwin Ziment, Miller Lg, Finegold Sm · PubMed · 1967 · 29 citations