BigBrain: An Ultrahigh-Resolution 3D Human Brain Model

TLDR

Reconstructing the human brain has become a standard research tool, with publicly available reference brains providing a macroscopic spatial framework (Amunts et al.). The authors aim to provide a freely available tool to aid interpretation of functional neuroimaging, fiber‑tract analyses, and molecular/genetic mapping. They present a 20 µm‑resolution three‑dimensional reconstruction of a human brain.

Abstract

Reconstructing the Human Brain Reference brains have become a standard tool in human brain research. Reference brains presently in the public domain provide a spatial framework at the macroscopic level. Amunts et al. (p. 1472 ) present a high-resolution (20 µm) three-dimensional reconstruction of a human brain. The tool will be freely available to help with interpreting functional neuroimaging studies, fiber tract analyses, and assigning molecular and gene expression data.