Medical and Pediatric Oncology · 1997 · 43 citations · 23 references
MedicineNeurosurgerySurgeryNeuro-oncologyPediatric OncologySurgical OncologyBrain TumorsCentral Nervous System TumorsPediatric Neuro-oncologySpinal Cord TumorsSpinal TumorsIntramedullary TumorsPediatric Spinal Cord TumorsPediatric Spinal Deformity
BACKGROUND: A retrospective review was carried out of nine children under 17 years of age with a diagnosis of intramedullary tumor seen during the period 1989-1995. Six had astrocytomas; one each had an ependymoma, a PNET, and a choroid plexus papilloma. Five patients had back pain, 3 others had mild pareses and the ninth had incapacitating defects. Seven of the 9 were treated by subtotal extirpation of the lesion, and biopsy alone was performed in the other two. All tumors were low grade (grade I or II) and therefore radiation therapy (RT) was performed as the only postoperative treatment in 8 of the 9 children. RESULTS: In February 1996, seven (77.8%) children were alive and two (22.2%) died of recurrent tumor (7 months and 5 years after diagnosis, respectively). Median follow-up was 3 years 4 months (range: 1 year 6 months to 7 years 3 months). CONCLUSION: Surgical removal of intraspinal tumors provides the best hope of control, but spinal column deformity after laminectomy and irradiation is a serious long-term problem in children. Orthopedic supervision for the prevention of these deformities; e.g., by external immobilization, is mandatory.
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Principles and Practice of Pediatric Oncology
Richard Labotka · JAMA · 1994 · 371 citations
Medicine, Oncology, Pediatrics +12
Radical resection of intramedullary spinal cord tumors in adults
Paul R. Cooper, Fred J. Epstein · Journal of neurosurgery · 1985 · 278 citations
Medicine, Neurosurgery, Surgery +15
Surgical Management of Intramedullary Spinal Cord Tumors
Loris Cristante, H. -D. Herrmann · Neurosurgery · 1994 · 240 citations
Medicine, Neurosurgery, Surgery +13