Curcumin Ameliorates Left Ventricular Function in Rabbits with Pressure Overload: Inhibition of the Remodeling of the Left Ventricular Collagen Network Associated with Suppression of Myocardial Tumor Necrosis Factor-.ALPHA. and Matrix Metalloproteinase-2 Expression

Abstract

Curcumin improved left ventricular function in pressure overloaded rabbits. This might be due to inhibition of collagen remodeling associated with suppression of myocardial expression of tumor necrosis factor-alpha, and matrix metalloproteinase-2.