Concepedia

VCP Is Essential for Mitochondrial Quality Control by PINK1/Parkin and this Function Is Impaired by VCP Mutations

Nam Chul Kim, Emilie Tresse, Regina‐Maria Kolaitis, Amandine Molliex, Ruth Thomas, Nael H. Alami, Bo Wang, Aashish Joshi, Rebecca B. Smith, Gillian P. Ritson,

Neuron · 2013 · 238 citations · 45 references

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45

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Derek P. Narendra, Atsushi Tanaka, Der‐Fen Suen et al. · The Journal of Cell Biology · 2008 · 4K citations · Full text

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PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Derek P. Narendra, Seok Min Jin, Atsushi Tanaka et al. · PLoS Biology · 2010 · 2.9K citations · Full text

, , +17

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

Noriyuki Matsuda, Shigeto Sato, Kahori Shiba et al. · The Journal of Cell Biology · 2010 · 1.9K citations · Full text

, , +17

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

Giles D. Watts, Jill Wymer, Margaret J. Kovach et al. · Nature Genetics · 2004 · 1.4K citations · Full text

, , +13

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

Atsushi Tanaka, Megan M. Cleland, Shan Xu et al. · The Journal of Cell Biology · 2010 · 1.3K citations · Full text

, , +17