Concepedia

Heterozygous familial hypercholesterolemia: Failure of normal allele to compensate for mutant allele at a regulated genetic locus

Joseph L. Goldstein, Mary K. Sobhani, Jerry R. Faust, Michael S. Brown

Cell · 1976 · 75 citations · 11 references

DOI

Concepts

References

11

Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts

Joseph L. Goldstein, Michael S. Brown · Journal of Biological Chemistry · 1974 · 1.5K citations · Full text

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Receptor-Mediated Control of Cholesterol Metabolism

Michael S. Brown, Joseph L. Goldstein · Science · 1976 · 963 citations

, , +14

Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans

Joseph L. Goldstein, Sandip K. Basu, Gloria Brunschede et al. · Cell · 1976 · 614 citations

, , +16

Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity in Cultured Human Fibroblasts

Michael S. Brown, Suzanna E. Dana, Joseph L. Goldstein · Journal of Biological Chemistry · 1974 · 543 citations · Full text

, , +17

Suppression of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity and Inhibition of Growth of Human Fibroblasts by 7-Ketocholesterol

Michael S. Brown, Joseph L. Goldstein · Journal of Biological Chemistry · 1974 · 500 citations · Full text

, , +17