A New Method for The Quantification of Neutrophil and Eosinophil Cationic Proteins in Feces: Establishment of Normal Levels and Clinical Application in Patients With Inflammatory Bowel Disease

Abstract

The method described here takes into account the molecular properties of the granule proteins and the heterogeneity in feces consistency, which is a prerequisite for a valid and reproducible measurement of cationic granule proteins. We suggest that EPX and myeloperoxidase, when applied in IBD, are the best eosinophil and neutrophil markers for studying GI inflammation.