Metabolic and histological features of non‐alcoholic fatty liver disease patients with different serum alanine aminotransferase levels

Abstract

Metabolic factors, but not ALT, are associated with histological severity. Patients with ALT < 0.5 x ULN may still have non-alcoholic steatohepatitis (NASH) and significant fibrosis. Evaluation of NAFLD patients should be based on metabolic risk factors, but not ALT level.