Concepedia

Methyl-Prostaglandin E<sub>2</sub>Analogues for Healing of Gastro-Duodenal Ulcers

J Rybicka, K Gibiński

Scandinavian Journal of Gastroenterology · 1978 · 55 citations · 8 references

DOI

Concepts

Abstract

117 patients were submitted to the randomized double-blind clinical trial. Methylated analogues of prostaglandin E2 administered orally markedly suppressed gastric acid secretion and--in comparison to placebo--accelerated cicatrization of duodenal ulcers, but not of gastric ulcers. The resistance of some ulcers to healing was not dependent on gastric acid secretion.

References

8

EFFECT OF 15(R)15 METHYLPROSTAGLANDIN E2 METHYL ESTER ON HEALING OF GASTRIC ULCERS

Wye–Poh Fung, S.M.M. Karim, C. Y. Tye · The Lancet · 1974 · 90 citations

, , +10

The Effect of 16,16-Dimethyl Prostaglandin E2 on Meal-Stimulated Gastric Acid Secretion and Serum Gastrin in Duodenal Ulcer Patients

Andrew Ippoliti, Jon I. Isenberg, V. Maxwell et al. · Gastroenterology · 1976 · 87 citations

, , +14

Double-blind clinical trial on gastroduodenal ulcer healing with prostaglandin E2 analogues.

K Gibiński, J Rybicka, E Mikoś et al. · Gut · 1977 · 83 citations · Full text

, , +15

Comparison of Methylated Prostaglandin E2 Analogues Given Orally in the Inhibition of Gastric Responses to Pentagastrin and Peptone Meal in Man

Stanisław J. Konturek, N Kwiecień, J Swierczek et al. · Gastroenterology · 1976 · 79 citations

, , +9

Effects of an Orally Administered Prostaglandin Analogue (16,16-Dimethyl Prostaglandin E2) on Human Gastric Secretion

Donald E. Wilson, Gerald Winnan, John Quertermus et al. · Gastroenterology · 1975 · 56 citations

, , +16