Biomechanical Analysis of Pedicle Screws in Osteoporotic Bone With Bioactive Cement Augmentation Using Simulated In Vivo Multicomponent Loading

Abstract

We believe our test protocol produced screw loosening failure similar to that observed clinically, and that it has the ability to detect differences in failure initiation force and failure modes to compare short-term efficacy of screw augmentation techniques. All cements improved screw resistance to failure. The CP > CS > M failure initiation force (P < 0.006) was because of differences in cement distribution. Animal studies may be required to characterize the remodeling activity of bioactive cements and their longer term efficacies.