Induction of testicular growth and spermatogenesis by pulsatile, intravenous administration of gonadotrophin‐releasing hormone in patients with hypogonadotrophic hypogonadism*

Abstract

GnRH is a feasible way to induce testicular growth as well as spermatogenesis in hypogonadotrophic male patients, even in patients in whom gonadotrophin treatment has failed. After GnRH treatment, hCG alone can maintain or even improve testicular development, including spermatogenesis. GnRH treatment may also induce a physiological growth spurt in hypogonadotrophic adolescents.