Gene expression profiles of lysophosphatidic acid‐related molecules in the prostate: Relevance to prostate cancer and benign hyperplasia

Abstract

By acting via LPA3, LPA may play an important role in the development of prostate cancer. Switching of LPA receptor expression from LPA3 to LPA1, may be involved in prostate cancer progression and/or androgen independence. LPA may also play a key role in the development of benign prostatic hyperplasia.