Acute cannabinoid receptor type 1 (CB1R) modulation influences insulin sensitivity by an effect outside the central nervous system in mice

mouse brain in stereotaxic coordinates

Keith B.J. Franklin, George Paxinos · 1997 · 3.1K citations

Medicine, Neurobiology, Neuroscience +9

Effects of Rimonabant on Metabolic Risk Factors in Overweight Patients with Dyslipidemia

Jean‐Pierre Després, Alain Golay, Lars Sjöström · New England Journal of Medicine · 2005 · 1.4K citations · Full text

Life Sciences, Biochemistry, Lipid Biochemistry +10

Effect of Rimonabant, a Cannabinoid-1 Receptor Blocker, on Weight and Cardiometabolic Risk Factors in Overweight or Obese Patients

F. Xavier Pi‐Sunyer, Louis J. Aronne, Hassan Heshmati et al. · JAMA · 2006 · 1.2K citations

Medicine, Pharmacology, Pharmacotherapy +17

The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis

Daniela Cota, Giovanni Marsicano, Matthias H. Tschöp et al. · Journal of Clinical Investigation · 2003 · 1.1K citations · Full text

Life Sciences, Neuroscience, Pharmacology +16

Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice

Andreas Zimmer, Anne Zimmer, Andrea G. Hohmann et al. · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations

Medicine, Neuroscience, Pharmacology +9