Developing a Methodology for Three-Dimensional Correlation of PET–CT Images and Whole-Mount Histopathology in Non-Small-Cell Lung Cancer

Abstract

There is no one definitive method for 3D volumetric RPC in nsclc. An innovative approach to the 3D reconstruction of resected nsclc specimens incorporates agar embedding of the specimen and whole-mount digital histopathology. The reconstructions can be rigidly and manually registered to imaging modalities such as ct and pet and exported to a radiation treatment planning system.