Anti‐cardiolipin from periodontitis patients induces <scp>MCP</scp>‐1 production by human umbilical vein endothelial cells

Abstract

Since elevated titres of anti-cardiolipin are found in a significantly greater proportion of patients with periodontitis than in periodontally healthy individuals, and these antibodies activate endothelial cells to produce monocyte chemotactic protein-1, they may explain some of the associations noted between periodontal infections and systemic conditions.