Room Temperature Palladium-Catalyzed Decarboxylative <i>ortho</i>-Acylation of Acetanilides with α-Oxocarboxylic Acids

Abstract

A novel Pd-catalyzed decarboxylative ortho-acylation of acetanilides with alpha-oxocarboxylic acids is realized at room temperature. This reaction provides efficient access to o-acyl acetanilides under mild conditions.