Methoxyflurane Metabolism and Renal Dysfunction

Abstract

Serun inorganic fluoride concentration and urinary inorganic fluoride and oxalic acid excretion were found to be markedly elevated in ten patients previously shown to have methoxyflurane-induced renal dysfunction. Five patients with climically evident renal dysfunction had a mean peak serum inorganic fluoride level (190.4 ± 20.9 μ/1) significantly higher (P