Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK

Publication | Open Access

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Citations

References

2009

Year

Maria J. Sambade, J. Terese Camp, Randall J. Kimple, Carolyn I. Sartor, Janiel M. Shields

Radiotherapy and Oncology

Radiation MedicineOncologyMedicineBreast Cancer CellsCancer Cell BiologyDirect InhibitionBreast CancerCell BiologyCancer TreatmentLapatinib-resistant CellsCancer BiologyRadiation OncologyTumor Biology