Symptomatic Hyponatremia in Association with a Low-Iodine Diet and Levothyroxine Withdrawal Prior to I ¹³¹ in Patients with Metastatic Thyroid Carcinoma

Abstract

The development of hyponatremia during LT4 withdrawal and low-iodine diet in otherwise healthy patients with thyroid carcinoma is extremely rare. However, elderly patients with metastatic thyroid carcinoma need observation during LT4 withdrawal combined with a low-iodine diet and should receive instruction to take iodine-free sodium chloride. Free water restriction may be necessary in some patients.