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Estrogen-Like Action of Tamoxifen on Vaginal Epithelium in Breast Cancer Patients
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1981
Year
Breast OncologyBreast Cancer ManagementGynecologyDermatologyMammary Gland DevelopmentTumor BiologyEstrogen-like ActionEstrogenic PropertiesOncologyBreast Cancer PatientsRadiation OncologyCancer ResearchOvarian HormoneEndocrine-related CancerVaginal EpitheliumBreast CancerMenopauseMedicineProlonged Administration
The action of prolonged administration of Tamoxifen on the vaginal epithelium in postmenopausal breast cancer patients has been investigated by means of exfoliative cytology. Our study gives quite convincing evidence of a clear-cut estrogenic effect of Tamoxifen on vaginal epithelium. The relationship between estrogenic properties of Tamoxifen and breast cancer management is discussed.