Narrow band imaging of squamous cell carcinoma tumors using topically delivered anti‐EGFR antibody conjugated gold nanorods

Abstract

We have demonstrated that a topical application of gold nanorods targeted specifically to tumor growth factor receptors results in a significantly higher image contrast compared to nontargeted gold nanorods. These results demonstrate the feasibility of near-infrared NBI to image and demarcate tumor margins during surgical resection using topical administration of targeted GNR.