The analysis and disposition of imipramine and its active metabolites in man

Statistical moments in pharmacokinetics

Kiyoshi Yamaoka, Terumichi Nakagawa, Toyozo Uno · Journal of Pharmacokinetics and Biopharmaceutics · 1978 · 1.3K citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +5

Bioavailability -- A Problem in Equivalence

Carl M. Metzler · Biometrics · 1974 · 638 citations

Pharmacy, Biostatistics, Pharmacology +10

A comparison of numerical integrating algorithms by trapezoidal, Lagrange, and spline approximation

K. C. Yeh, K.C. Kwan · Journal of Pharmacokinetics and Biopharmaceutics · 1978 · 430 citations

Computing, Computational Engineering, Computer Science +12

Plasma protein binding of basic drugs. I. Selective displacement from alpha 1-acid glycoprotein by tris(2-butoxyethyl) phosphate.

Kenneth M. Piafsky, Odd G. Nilsen · PubMed · 1977 · 161 citations

Medicine, Pharmaceutics, Pharmacology +13

First‐pass metabolism of imipramine in man

Lars F. Gram, Johannes Christiansen · Clinical Pharmacology & Therapeutics · 1975 · 120 citations

Pharmacy, Pharmacokinetics, Pharmacology +10