Influence of Iodine-131 Dose on the Outcome of Hyperthyroidism in Children

Abstract

We found that doses of 100 Gy (110 microCi/g), 200 Gy (220 microCi/g), and 300 Gy (330 microCi/g) resulted in hypothyroidism in 50%, 70%, and 95% of treated individuals, respectively. These data show that to insure ablation of thyroid tissue doses, >270 Gy (300 microCi/g) is needed, especially when the thyroid is large.