Alloimmunization and Erythrocyte Autoimmunization in Transfusion-dependent Egyptian Thalassemic Patients

Abstract

Alloimmunization to RBCs' antigens is a frequent finding among Egyptian transfusion-dependent thalassemic patients, with the majority of patients being transfused with blood matched for ABO and D antigens only. Absence of phenotypically matched donors, except for a limited number of patients, may have contributed to this problem.